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GENEWIZ Blog

GENEWIZ from Azenta Life Sciences presents a series of educational articles about genomics and the technologies behind nucleic acid (DNA and RNA) sequencing and synthesis.

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  • rna sequencing
  • rna therapeutics
  • mRNA
  • aav-itr
  • itr sequencing
  • aav plasmid prep
  • gene synthesis
  • next generation sequencing
  • rna sequencing
  • transcriptomics
  • sanger sequencing
  • whole plasmid sequencing
  • oxford nanopore sequencing (ont)
  • proteomics
  • cell and gene therapy
  • gene synthesis
  • circular rna (circRNA)
  • rna therapeutics
  • quantitative pcr (qPCR)
  • pcr + sanger sequencing
  • gene synthesis
  • lentivirus
  • antibody discovery
  • gene synthesis
  • itr sequencing
  • cell and gene therapy
  • digital pcr (dPCR)
  • quantitative pcr (qPCR)
  • PacBio
  • long-read sequencing
  • single-cell sequencing
Fine-Tuning mRNA Structure for Better mRNA Therapies

The structure of mRNA has been known for decades, but only in recent years have researchers unlocked its potential for ...

GENEWIZ

GENEWIZ

March 07, 2025
AAV Vectors in Gene Therapy: Measuring & Optimizing Quality

Adeno-associated viruses (AAV) are promising vectors for in vivo gene therapy. They can deliver a genetic payload of up to 4.7 kb ...

GENEWIZ

GENEWIZ

February 26, 2025
How to Improve Your RNA-Seq Data with UMIs and ERCC RNA

Quantifying transcripts accurately and reproducibly is critical when studying gene expression. Scientists have developed two ...

GENEWIZ

GENEWIZ

February 24, 2025
Troubleshooting DNA Templates with Sanger Sequencing

Sanger sequencing is highly effective for testing small targeted genomic regions and for validating results from NGS. However, as ...

Annie Huang

Annie Huang

February 24, 2025
Complete Plasmid Validation with Oxford Nanopore Sequencing

In the current sequencing landscape, there are two major technologies that are often used to read the nucleotide bases in plasmid ...

The Power of Proteomics

The landscape of drug development is constantly evolving, fueled by groundbreaking scientific advancements. While genetics has ...

GENEWIZ

GENEWIZ

February 24, 2025
Circular RNA: An Emerging Frontier in RNA Therapeutics

Circular RNA (circRNA), a covalently closed single-stranded RNA molecule, has rapidly gained traction in the research and ...

GENEWIZ

GENEWIZ

February 21, 2025
The Brewer’s Genomic Toolbox for Better Beer

Brewing beer is a complex process that requires careful control of its parameters, including the yeast strains used for ...

GENEWIZ

GENEWIZ

February 21, 2025
Comparing Mass Spectrometry, ELISA, and Olink for Proteomics

The field of proteomics has evolved significantly in the last decade, with several technologies now available to assay protein ...

Bhagyashree Birla

Bhagyashree Birla

February 21, 2025
Using Forensic Science to Catch Elephant Poachers

Ivory is a highly valuable material found in the tusks of hippopotamuses, walruses, and other animals, but is most commonly – and ...

GENEWIZ

GENEWIZ

February 20, 2025
Using Synthetic Biology to Understand the Evolution of Bacterial Resistance

Antimicrobial resistance represents one of the major global threats to health and development. Mutations are the driving force of ...

Mato Lagator, Ph.D.

Mato Lagator, Ph.D.

February 20, 2025
How Olink® Technology Is Revolutionizing Proteomics and Multiomics

The development of scalable and sensitive technologies, such as next generation sequencing (NGS) and quantitative PCR (qPCR), has ...

GENEWIZ

GENEWIZ

February 20, 2025
Lentivirus Production for Gene Delivery

With the emergence of cell and gene therapy and other gene editing technologies, interest in efficient and effective gene ...

GENEWIZ

GENEWIZ

February 20, 2025
A Beginner’s Guide to Artificial DNA Synthesis

Basics of Synthetic DNA and Gene Synthesis Artificial DNA synthesis, a fundamental tool of synthetic biology, enables scientists ...

GENEWIZ

GENEWIZ

February 19, 2025
Monoclonal Antibody Production: Hybridoma vs. Recombinant

Antibodies are specialized proteins produced by the immune system that bind and neutralize foreign invaders such as viruses, ...

GENEWIZ

GENEWIZ

February 19, 2025
Antibody Libraries for In Vitro Display: What to Consider

The strength of any display-based antibody discovery program hinges on its library. While all library types have the potential to ...

GENEWIZ

GENEWIZ

February 19, 2025
Clearing Roadblocks in Early-Stage Cell & Gene Therapy Development

Under intense pressure to develop cell and gene therapies on tight timelines, biotech companies are encountering common ...

Conrad Leung

Conrad Leung

February 19, 2025
NGS, qPCR, or Sanger Sequencing: An Assay Selection Guide

Interactive Assay Selection Tool

GENEWIZ

GENEWIZ

February 19, 2025
A Quick Start Guide to RNA-Seq Data Analysis

The ultimate value of an RNA-Seq experiment comes from data analysis. Next generation sequencing (NGS) experiments generate a ...

GENEWIZ

GENEWIZ

February 18, 2025
PacBio HiFi Sequencing for Understanding Human Health and Disease

GENEWIZ and PacBio® held a virtual symposium titled Decoding the Complexity of Human Health – A HiFi Vision on October 5, 2021 ...

GENEWIZ

GENEWIZ

February 18, 2025
Optimizing AAV Plasmid Preparation and ITR Sequencing

The adeno-associated virus (AAV) is a powerful vehicle for gene therapy; however, working with AAV vectors can be challenging. ...

GENEWIZ

GENEWIZ

February 18, 2025
Stranded vs Non-Stranded RNA-Seq

RNA-Seq libraries can be stranded or non-stranded (unstranded). How you prepare the libraries affects the data generated from ...

GENEWIZ

GENEWIZ

February 18, 2025
Analyzing Sanger Sequencing Data

The output for Sanger sequencing is typically a chromatogram, also known as a trace or ab1 file, and a text-based sequence file. ...

GENEWIZ

GENEWIZ

February 17, 2025
RNA-Seq Selection Guide: How to Start Designing Your Project

RNA sequencing (RNA-Seq) is the most popular type of next generation sequencing (NGS) approach, enabling researchers to study the ...

GENEWIZ

GENEWIZ

February 17, 2025
Single-Cell Sequencing: Top 3 Factors to Consider

Thinking about leveraging single-cell sequencing for your research? You’re not alone. Named Method of the Year in 2013 by ...

GENEWIZ

GENEWIZ

February 17, 2025
How Single-Cell Sequencing Works

Single-cell sequencing has changed markedly since its first publication in 20091. In that seminal study, researchers manually ...

GENEWIZ

GENEWIZ

February 17, 2025